Single nucleotide polymorphism 1623 A/G (rs180195) in the promoter of the Thyroglobulin gene is associated with autoimmune thyroid disease but not with thyroid ophthalmopathy

BACKGROUND: Our studies over recent years have focused on some new ideas concerning the pathogenesis for the orbital reaction that characterizes Graves’ ophthalmopathy namely, that there are antigens expressed by thyroid tissue and orbital tissue where they are targeted by autoantibodies and/or sens...

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Detalles Bibliográficos
Autores principales: Lahooti, Hooshang, Edirimanne, Senarath, Walsh, John P, Delbridge, Leigh, Hibbert, Emily J, Wall, Jack R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536092/
https://www.ncbi.nlm.nih.gov/pubmed/28794611
http://dx.doi.org/10.2147/OPTH.S136070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536092/
https://www.ncbi.nlm.nih.gov/pubmed/28794611
http://dx.doi.org/10.2147/OPTH.S136070

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