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Combination therapy with ampicillin and azithromycin improved outcomes in a mouse model of group B streptococcal sepsis

BACKGROUND: Evidence suggests that β-lactam monotherapy of streptococcal infections may incite stronger inflammation and is inferior to combination therapy with macrolides. We hypothesized that use of macrolides alone or in combination with a β-lactam for group B streptococcal (GBS) sepsis would imp...

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Detalles Bibliográficos
Autores principales: Upadhyay, Kirtikumar, Hiregoudar, Basu, Meals, Elizabeth, English, Boyce Keith, Talati, Ajay J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536305/
https://www.ncbi.nlm.nih.gov/pubmed/28759625
http://dx.doi.org/10.1371/journal.pone.0182023