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Combination therapy with ampicillin and azithromycin improved outcomes in a mouse model of group B streptococcal sepsis
BACKGROUND: Evidence suggests that β-lactam monotherapy of streptococcal infections may incite stronger inflammation and is inferior to combination therapy with macrolides. We hypothesized that use of macrolides alone or in combination with a β-lactam for group B streptococcal (GBS) sepsis would imp...
Autores principales: | Upadhyay, Kirtikumar, Hiregoudar, Basu, Meals, Elizabeth, English, Boyce Keith, Talati, Ajay J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536305/ https://www.ncbi.nlm.nih.gov/pubmed/28759625 http://dx.doi.org/10.1371/journal.pone.0182023 |
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