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P2Y(12) and P2Y(13) receptors involved in ADPβs induced the release of IL-1β, IL-6 and TNF-α from cultured dorsal horn microglia

OBJECTIVE: P2 receptors have been implicated in the release of neurotransmitter and pro-inflammatory cytokines due to their response to neuroexcitatory substances in the microglia. Dorsal horn P2Y(12) and P2Y(13) receptors are involved in the development of pain behavior induced by peripheral nerve...

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Detalles Bibliográficos
Autores principales: Liu, Pei-Wen, Yue, Ming-Xia, Zhou, Rui, Niu, Juan, Huang, Du-Juan, Xu, Tao, Luo, Pei, Liu, Xiao-Hong, Zeng, Jun-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536317/
https://www.ncbi.nlm.nih.gov/pubmed/28794655
http://dx.doi.org/10.2147/JPR.S137131