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P2Y(12) and P2Y(13) receptors involved in ADPβs induced the release of IL-1β, IL-6 and TNF-α from cultured dorsal horn microglia
OBJECTIVE: P2 receptors have been implicated in the release of neurotransmitter and pro-inflammatory cytokines due to their response to neuroexcitatory substances in the microglia. Dorsal horn P2Y(12) and P2Y(13) receptors are involved in the development of pain behavior induced by peripheral nerve...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536317/ https://www.ncbi.nlm.nih.gov/pubmed/28794655 http://dx.doi.org/10.2147/JPR.S137131 |