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A unique enhancer boundary complex on the mouse ribosomal RNA genes persists after loss of Rrn3 or UBF and the inactivation of RNA polymerase I transcription

Transcription of the several hundred of mouse and human Ribosomal RNA (rRNA) genes accounts for the majority of RNA synthesis in the cell nucleus and is the determinant of cytoplasmic ribosome abundance, a key factor in regulating gene expression. The rRNA genes, referred to globally as the rDNA, ar...

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Detalles Bibliográficos
Autores principales: Herdman, Chelsea, Mars, Jean-Clement, Stefanovsky, Victor Y., Tremblay, Michel G., Sabourin-Felix, Marianne, Lindsay, Helen, Robinson, Mark D., Moss, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536353/
https://www.ncbi.nlm.nih.gov/pubmed/28715449
http://dx.doi.org/10.1371/journal.pgen.1006899