Downregulation of SMC1A inhibits growth and increases apoptosis and chemosensitivity of colorectal cancer cells

OBJECTIVE: The structural maintenance of chromosomes (SMC) 1A protein is a component of the cohesin multiprotein complex that is essential for sister chromatid cohesion. SMC1A gene mutations have been reported in colorectal cancer. This study aimed to investigate the role of SMC1A gene expression in...

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Detalles Bibliográficos
Autores principales: Li, Jin, Feng, Wanting, Chen, Longbang, He, Jingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536575/
https://www.ncbi.nlm.nih.gov/pubmed/26637483
http://dx.doi.org/10.1177/0300060515600188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536575/
https://www.ncbi.nlm.nih.gov/pubmed/26637483
http://dx.doi.org/10.1177/0300060515600188

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