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Cryptotanshinone potentiates the antitumor effects of doxorubicin on gastric cancer cells via inhibition of STAT3 activity

OBJECTIVE: To investigate the synergistic effects of cryptotanshinone (CPT) and doxorubicin (DOXO) on induction of apoptosis in human gastric cancer cells and the mechanisms. METHODS: Cell proliferation and apoptosis were detected using the CCK8 assay and AnnexinV/PI staining, respectively. Western...

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Detalles Bibliográficos
Autores principales: Wang, Jiye, Zhang, Guangji, Dai, Chunyan, Gao, Xiufei, Wu, Jianbin, Shen, Li, Chen, Zhe, Liu, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536615/
https://www.ncbi.nlm.nih.gov/pubmed/28222632
http://dx.doi.org/10.1177/0300060516685513