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Heparanase overexpression down-regulates syndecan-1 expression in a gallbladder carcinoma cell line

OBJECTIVE: To discuss the relevance of heparanase and syndecan-1 and regulation of the heparanase-syndecan1 axis in the invasiveness of gallbladder carcinoma cells. METHODS: 1. Generation of a gallbladder cancer cell line overexpressing a heparanase (GBD-SD) transgene. 2. Western blot analysis of sy...

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Detalles Bibliográficos
Autores principales: Jin, Hao, Zhou, Shaobo, Yang, Song, Cao, Hai-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536678/
https://www.ncbi.nlm.nih.gov/pubmed/28351285
http://dx.doi.org/10.1177/0300060517700323