Cargando…

Heparanase overexpression down-regulates syndecan-1 expression in a gallbladder carcinoma cell line

OBJECTIVE: To discuss the relevance of heparanase and syndecan-1 and regulation of the heparanase-syndecan1 axis in the invasiveness of gallbladder carcinoma cells. METHODS: 1. Generation of a gallbladder cancer cell line overexpressing a heparanase (GBD-SD) transgene. 2. Western blot analysis of sy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jin, Hao, Zhou, Shaobo, Yang, Song, Cao, Hai-ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2017
Materias:	Research Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536678/ https://www.ncbi.nlm.nih.gov/pubmed/28351285 http://dx.doi.org/10.1177/0300060517700323

Ejemplares similares

Heparanase Regulates Levels of Syndecan-1 in the Nucleus
por: Chen, Ligong, et al.
Publicado: (2009)

Loss of Syndecan‐1 and Increased Expression of Heparanase in Invasive Esophageal Carcinomas
por: Mikami, Shuji, et al.
Publicado: (2001)

Immunohistochemical Expression of Heparanase Isoforms and Syndecan-1 Proteins in Colorectal Adenomas
por: Waisberg, J., et al.
Publicado: (2016)

Heparanase activates the syndecan-syntenin-ALIX exosome pathway
por: Roucourt, Bart, et al.
Publicado: (2015)

High glucose-induced intestinal epithelial barrier damage is aggravated by syndecan-1 destruction and heparanase overexpression
por: Qing, Qing, et al.
Publicado: (2015)

Heparanase and Syndecan-4 Are Involved in Low Molecular Weight Fucoidan-Induced Angiogenesis
por: Haddad, Oualid, et al.
Publicado: (2015)

Role of Heparanase and Syndecan-1 in HSV-1 Release from Infected Cells
por: Sharma, Pankaj, et al.
Publicado: (2022)

A positive feedback loop of heparanase/syndecan1/nerve growth factor regulates cancer pain progression
por: Su, Xiaohu, et al.
Publicado: (2023)

Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin
por: Ma, Peisong, et al.
Publicado: (2006)

Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin
por: Ma, Peisong, et al.
Publicado: (2011)

Allele Loss and Down-Regulation of Heparanase Gene Are Associated with the Progression and Poor Prognosis of Hepatocellular Carcinoma
por: Huang, Guo-Liang, et al.
Publicado: (2012)

Protease, Growth Factor, and Heparanase-Mediated Syndecan-1 Shedding Leads to Enhanced HSV-1 Egress
por: Karasneh, Ghadah A., et al.
Publicado: (2021)

Heparanase Promotes Syndecan-1 Expression to Mediate Fibrillar Collagen and Mammographic Density in Human Breast Tissue Cultured ex vivo
por: Huang, Xuan, et al.
Publicado: (2020)

Expressions of heparanase and upstream stimulatory factor in hepatocellular carcinoma
por: Chen, Bin, et al.
Publicado: (2014)

Syndecan-1-Dependent Regulation of Heparanase Affects Invasiveness, Stem Cell Properties, and Therapeutic Resistance of Caco2 Colon Cancer Cells
por: Katakam, Sampath Kumar, et al.
Publicado: (2020)

Regulation of Heparanase in Diabetes-Associated Pancreatic Carcinoma
por: Goldberg, Rachel, et al.
Publicado: (2019)

Corrigendum: Heparanase Promotes Syndecan-1 Expression to Mediate Fibrillar Collagen and Mammographic Density in Human Breast Tissue Cultured ex vivo
por: Huang, Xuan, et al.
Publicado: (2021)

Overexpression of heparanase attenuated TGF‐β‐stimulated signaling in tumor cells
por: Batool, Tahira, et al.
Publicado: (2017)

Expression of heparanase in basal cell carcinoma and squamous cell carcinoma
por: Pinhal, Maria Aparecida Silva, et al.
Publicado: (2016)

microRNA-145 promotes differentiation in human urothelial carcinoma through down-regulation of syndecan-1
por: Fujii, Tomomi, et al.
Publicado: (2015)

Heparanase Overexpresses in Keratoconic Cornea and Tears Depending on the Pathologic Grade
por: García, Beatriz, et al.
Publicado: (2017)

Heparanase Overexpression Reduces Hepcidin Expression, Affects Iron Homeostasis and Alters the Response to Inflammation
por: Asperti, Michela, et al.
Publicado: (2016)

Newly Generated Heparanase Knock-Out Mice Unravel Co-Regulation of Heparanase and Matrix Metalloproteinases
por: Zcharia, Eyal, et al.
Publicado: (2009)

Heparanase-induced shedding of syndecan-1/CD138 in myeloma and endothelial cells activates VEGFR2 and an invasive phenotype: prevention by novel synstatins
por: Jung, O, et al.
Publicado: (2016)

Prognostic significance of heparanase expression in primary and metastatic breast carcinoma
por: Vornicova, Olga, et al.
Publicado: (2017)

Heparanase expression upregulates platelet adhesion activity and thrombogenicity
por: Cui, Hao, et al.
Publicado: (2016)

Glucose-regulated protein 78 and heparanase expression in oral squamous cell carcinoma: correlations and prognostic significance
por: Xia, Fei, et al.
Publicado: (2014)

Suramin inhibits cell proliferation in ovarian and cervical cancer by downregulating heparanase expression
por: Li, HuaPing, et al.
Publicado: (2015)

Heparanase 2 expression inversely correlates with bladder carcinoma grade and stage
por: Gross-Cohen, Miriam, et al.
Publicado: (2016)

Increased chemotactic migration and growth in heparanase-overexpressing human U251n glioma cells
por: Hong, Xin, et al.
Publicado: (2008)

Down-Regulated Phosphoglycerate Kinase 1 Expression Is Associated With Poor Prognosis in Patients With Gallbladder Cancer
por: Lu, Wei, et al.
Publicado: (2015)

Syndecan-1 and FGF-2, but Not FGF Receptor-1, Share a Common Transport Route and Co-Localize with Heparanase in the Nuclei of Mesenchymal Tumor Cells
por: Zong, Fang, et al.
Publicado: (2009)

Syndecan-Regulated Receptor Signaling
por: Rapraeger, Alan C.
Publicado: (2000)

Salmonella alters heparanase expression and reduces tumor metastasis
por: Chiu, Huan-Min, et al.
Publicado: (2021)

Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain
por: Zhang, Xiao, et al.
Publicado: (2012)

Expression of heparanase in soft tissue sarcomas of adults
por: Kazarin, Olga, et al.
Publicado: (2014)

The prognostic significance of heparanase expression in metastatic melanoma
por: Vornicova, Olga, et al.
Publicado: (2016)

The Profile of Heparanase Expression Distinguishes Differentiated Thyroid Carcinoma from Benign Neoplasms
por: Matos, Leandro Luongo, et al.
Publicado: (2015)

Systemic LPS-induced Aβ-solubilization and clearance in AβPP-transgenic mice is diminished by heparanase overexpression
por: Jendresen, Charlotte, et al.
Publicado: (2019)

Overexpression of heparanase enhances T lymphocyte activities and intensifies the inflammatory response in a model of murine rheumatoid arthritis
por: Digre, Andreas, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_m1dpooe129jbe08qbgoar4oppq