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Defective Hand1 phosphoregulation uncovers essential roles for Hand1 in limb morphogenesis

The morphogenesis of the vertebrate limbs is a complex process in which cell signaling and transcriptional regulation coordinate diverse structural adaptations in diverse species. In this study, we examine the consequences of altering Hand1 dimer choice regulation within developing vertebrate limbs....

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Detalles Bibliográficos
Autores principales: Firulli, Beth A., Milliar, Hannah, Toolan, Kevin P., Harkin, Jade, Fuchs, Robyn K., Robling, Alex G., Firulli, Anthony B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536869/
https://www.ncbi.nlm.nih.gov/pubmed/28576769
http://dx.doi.org/10.1242/dev.149963