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Proteostasis, oxidative stress and aging

The production of reactive species is an inevitable by-product of metabolism and thus, life itself. Since reactive species are able to damage cellular structures, especially proteins, as the most abundant macromolecule of mammalian cells, systems are necessary which regulate and preserve a functiona...

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Detalles Bibliográficos
Autores principales: Korovila, Ioanna, Hugo, Martín, Castro, José Pedro, Weber, Daniela, Höhn, Annika, Grune, Tilman, Jung, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536880/
https://www.ncbi.nlm.nih.gov/pubmed/28763764
http://dx.doi.org/10.1016/j.redox.2017.07.008