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Identification of transcriptome signature for myocardial reductive stress

The nuclear factor erythroid 2 like 2 (Nfe2l2/Nrf2) is a master regulator of antioxidant gene transcription. We recently identified that constitutive activation of Nrf2 (CaNrf2) caused reductive stress (RS) in the myocardium. Here we investigate how chronic Nrf2 activation alters myocardial mRNA tra...

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Detalles Bibliográficos
Autores principales: Quiles, Justin M., Narasimhan, Madhusudhanan, Mosbruger, Timothy, Shanmugam, Gobinath, Crossman, David, Rajasekaran, Namakkal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536881/
https://www.ncbi.nlm.nih.gov/pubmed/28768233
http://dx.doi.org/10.1016/j.redox.2017.07.013