Psoriasiform skin disease in transgenic pigs with high-copy ectopic expression of human integrins α2 and β1

Psoriasis is a complex human-specific disease characterized by perturbed keratinocyte proliferation and a pro-inflammatory environment in the skin. Porcine skin architecture and immunity are very similar to that in humans, rendering the pig a suitable animal model for studying the biology and treatm...

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Detalles Bibliográficos
Autores principales: Staunstrup, Nicklas Heine, Stenderup, Karin, Mortensen, Sidsel, Primo, Maria Nascimento, Rosada, Cecilia, Steiniche, Torben, Liu, Ying, Li, Rong, Schmidt, Mette, Purup, Stig, Dagnæs-Hansen, Frederik, Schrøder, Lisbeth Dahl, Svensson, Lars, Petersen, Thomas Kongstad, Callesen, Henrik, Bolund, Lars, Mikkelsen, Jacob Giehm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536904/
https://www.ncbi.nlm.nih.gov/pubmed/28679670
http://dx.doi.org/10.1242/dmm.028662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536904/
https://www.ncbi.nlm.nih.gov/pubmed/28679670
http://dx.doi.org/10.1242/dmm.028662

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