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Psoriasiform skin disease in transgenic pigs with high-copy ectopic expression of human integrins α2 and β1
Psoriasis is a complex human-specific disease characterized by perturbed keratinocyte proliferation and a pro-inflammatory environment in the skin. Porcine skin architecture and immunity are very similar to that in humans, rendering the pig a suitable animal model for studying the biology and treatm...
| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536904/ https://www.ncbi.nlm.nih.gov/pubmed/28679670 http://dx.doi.org/10.1242/dmm.028662 |