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An alternative surgical approach reduces variability following filament induction of experimental stroke in mice

Animal models are essential for understanding the pathology of stroke and investigating potential treatments. However, in vivo stroke models are associated, particularly in mice, with high variability in lesion volume. We investigated whether a surgical refinement where reperfusion is not reliant on...

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Detalles Bibliográficos
Autores principales: Trotman-Lucas, Melissa, Kelly, Michael E., Janus, Justyna, Fern, Robert, Gibson, Claire L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536906/
https://www.ncbi.nlm.nih.gov/pubmed/28550100
http://dx.doi.org/10.1242/dmm.029108