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A tripeptidyl peptidase 1 is a binding partner of the Golgi pH regulator (GPHR) in Dictyostelium

Mutations in tripeptidyl peptidase 1 (TPP1) have been associated with late infantile neuronal ceroid lipofuscinosis (NCL), a neurodegenerative disorder. TPP1 is a lysosomal serine protease, which removes tripeptides from the N-terminus of proteins and is composed of an N-terminal prodomain and a cat...

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Detalles Bibliográficos
Autores principales: Stumpf, Maria, Müller, Rolf, Gaßen, Berthold, Wehrstedt, Regina, Fey, Petra, Karow, Malte A., Eichinger, Ludwig, Glöckner, Gernot, Noegel, Angelika A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536908/
https://www.ncbi.nlm.nih.gov/pubmed/28546289
http://dx.doi.org/10.1242/dmm.029280