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A tripeptidyl peptidase 1 is a binding partner of the Golgi pH regulator (GPHR) in Dictyostelium
Mutations in tripeptidyl peptidase 1 (TPP1) have been associated with late infantile neuronal ceroid lipofuscinosis (NCL), a neurodegenerative disorder. TPP1 is a lysosomal serine protease, which removes tripeptides from the N-terminus of proteins and is composed of an N-terminal prodomain and a cat...
Autores principales: | Stumpf, Maria, Müller, Rolf, Gaßen, Berthold, Wehrstedt, Regina, Fey, Petra, Karow, Malte A., Eichinger, Ludwig, Glöckner, Gernot, Noegel, Angelika A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536908/ https://www.ncbi.nlm.nih.gov/pubmed/28546289 http://dx.doi.org/10.1242/dmm.029280 |
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