Generation of a multipurpose Prdm16 mouse allele by targeted gene trapping

Gene trap mutagenesis is a powerful tool to create loss-of-function mutations in mice and other model organisms. Modifications of traditional gene trap cassettes, including addition of conditional features in the form of Flip-excision (FlEx) arrays to enable directional gene trap cassette inversions...

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Detalles Bibliográficos
Autores principales: Strassman, Alexander, Schnütgen, Frank, Dai, Qi, Jones, Jennifer C., Gomez, Angela C., Pitstick, Lenore, Holton, Nathan E., Moskal, Russell, Leslie, Erin R., von Melchner, Harald, Beier, David R., Bjork, Bryan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Resource Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536910/
https://www.ncbi.nlm.nih.gov/pubmed/28424158
http://dx.doi.org/10.1242/dmm.029561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536910/
https://www.ncbi.nlm.nih.gov/pubmed/28424158
http://dx.doi.org/10.1242/dmm.029561

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