Parallel imaging of Drosophila embryos for quantitative analysis of genetic perturbations of the Ras pathway

The Ras pathway patterns the poles of the Drosophila embryo by downregulating the levels and activity of a DNA-binding transcriptional repressor Capicua (Cic). We demonstrate that the spatiotemporal pattern of Cic during this signaling event can be harnessed for functional studies of mutations in th...

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Detalles Bibliográficos
Autores principales: Goyal, Yogesh, Levario, Thomas J., Mattingly, Henry H., Holmes, Susan, Shvartsman, Stanislav Y., Lu, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Resource Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536913/
https://www.ncbi.nlm.nih.gov/pubmed/28495673
http://dx.doi.org/10.1242/dmm.030163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536913/
https://www.ncbi.nlm.nih.gov/pubmed/28495673
http://dx.doi.org/10.1242/dmm.030163

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