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Mechanisms mitigating problems associated with multiple kinetochores on one microtubule in early mitosis

Proper chromosome segregation in mitosis relies on correct kinetochore interaction with spindle microtubules. In early mitosis, each kinetochore usually interacts with the lateral side of each microtubule and is subsequently tethered at the microtubule end. However, since eukaryotic cells carry mult...

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Detalles Bibliográficos
Autores principales: Yue, Zuojun, Komoto, Shinya, Gierlinski, Marek, Pasquali, Debora, Kitamura, Etsushi, Tanaka, Tomoyuki U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536920/
https://www.ncbi.nlm.nih.gov/pubmed/28546446
http://dx.doi.org/10.1242/jcs.203000