CtBP- an emerging oncogene and novel small molecule drug target: Advances in the understanding of its oncogenic action and identification of therapeutic inhibitors

C-terminal Binding Proteins (CtBP) 1 and 2 are oncogenic transcriptional co-regulators overexpressed in many cancer types, with their expression level correlating to worse prognostic outcomes and aggressive tumor features. CtBP negatively regulates the expression of many tumor suppressor genes, whil...

Descripción completa

Detalles Bibliográficos
Autores principales: Dcona, M. Michael, Morris, Benjamin L., Ellis, Keith C., Grossman, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536941/
https://www.ncbi.nlm.nih.gov/pubmed/28532298
http://dx.doi.org/10.1080/15384047.2017.1323586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536941/
https://www.ncbi.nlm.nih.gov/pubmed/28532298
http://dx.doi.org/10.1080/15384047.2017.1323586

Ejemplares similares