Novel inhibition of PIM2 kinase has significant anti-tumor efficacy in multiple myeloma

The PIM kinase family (PIM1, 2 and 3) play a central role in integrating growth and survival signals, and are expressed in a wide range of solid and hematological malignancies. We now confirm that PIM2 is overexpressed in multiple myeloma (MM) patients, and within MM group it is overexpressed in the...

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Detalles Bibliográficos
Autores principales: Nair, Jayakumar R., Caserta, Justin, Belko, Krista, Howell, Tyger, Fetterley, Gerald, Baldino, Carmen, Lee, Kelvin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537056/
https://www.ncbi.nlm.nih.gov/pubmed/28008178
http://dx.doi.org/10.1038/leu.2016.379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537056/
https://www.ncbi.nlm.nih.gov/pubmed/28008178
http://dx.doi.org/10.1038/leu.2016.379

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