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Endoglucanase activity at a second site in Pyrococcus furiosus triosephosphate isomerase—Promiscuity or compensation for a metabolic handicap?

The eight‐stranded (β/α)(8) barrel fold known as the Triosephosphate isomerase (TIM) barrel is the most commonly observed fold in enzymes, displaying an eightfold structural symmetry. The sequences and structures of different TIM barrel enzymes suggest that nature exploits the modularity inherent in...

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Detalles Bibliográficos
Autores principales: Sharma, Prerna, Guptasarma, Purnananda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537068/
https://www.ncbi.nlm.nih.gov/pubmed/28781953
http://dx.doi.org/10.1002/2211-5463.12249