ErbB2 signaling epigenetically suppresses microRNA‐205 transcription via Ras/Raf/MEK/ERK pathway in breast cancer

We previously reported that microRNA‐205 (miR‐205) is downregulated by overexpression of the receptor tyrosine kinase ErbB2 and that ectopic transfection of miR‐205 precursor decreases ErbB2 tumorigenicity in soft agar. In this study, we further analyzed the regulatory mechanisms linking ErbB2 overe...

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Detalles Bibliográficos
Autores principales: Hasegawa, Takuya, Adachi, Ryohei, Iwakata, Hitoshi, Takeno, Takayoshi, Sato, Koji, Sakamaki, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537069/
https://www.ncbi.nlm.nih.gov/pubmed/28781955
http://dx.doi.org/10.1002/2211-5463.12256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537069/
https://www.ncbi.nlm.nih.gov/pubmed/28781955
http://dx.doi.org/10.1002/2211-5463.12256

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