Fibroblast-derived CXCL12/SDF-1α promotes CXCL6 secretion and co-operatively enhances metastatic potential through the PI3K/Akt/mTOR pathway in colon cancer

AIM: To investigate the underlying mechanism by which CXCL12 and CXCL6 influences the metastatic potential of colon cancer and internal relation of colon cancer and stromal cells. METHODS: Western blotting was used to detect the expression of CXCL12 and CXCL6 in colon cancer cells and stromal cells....

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Detalles Bibliográficos
Autores principales: Ma, Jia-Chi, Sun, Xiao-Wen, Su, He, Chen, Quan, Guo, Tian-Kang, Li, Yuan, Chen, Xiao-Chang, Guo, Jin, Gong, Zhen-Qiang, Zhao, Xiao-Dan, Qi, Jian-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537183/
https://www.ncbi.nlm.nih.gov/pubmed/28811711
http://dx.doi.org/10.3748/wjg.v23.i28.5167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537183/
https://www.ncbi.nlm.nih.gov/pubmed/28811711
http://dx.doi.org/10.3748/wjg.v23.i28.5167

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