Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice

Dietary restriction regimes extend lifespan in various animal models. Here we show that longevity in male C57BL/6J mice subjected to every-other-day feeding is associated with a delayed onset of neoplastic disease that naturally limits lifespan in these animals. We compare more than 200 phenotypes i...

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Detalles Bibliográficos
Autores principales: Xie, Kan, Neff, Frauke, Markert, Astrid, Rozman, Jan, Aguilar-Pimentel, Juan Antonio, Amarie, Oana Veronica, Becker, Lore, Brommage, Robert, Garrett, Lillian, Henzel, Kristin S., Hölter, Sabine M., Janik, Dirk, Lehmann, Isabelle, Moreth, Kristin, Pearson, Brandon L., Racz, Ildiko, Rathkolb, Birgit, Ryan, Devon P., Schröder, Susanne, Treise, Irina, Bekeredjian, Raffi, Busch, Dirk H., Graw, Jochen, Ehninger, Gerhard, Klingenspor, Martin, Klopstock, Thomas, Ollert, Markus, Sandholzer, Michael, Schmidt-Weber, Carsten, Weiergräber, Marco, Wolf, Eckhard, Wurst, Wolfgang, Zimmer, Andreas, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabě de Angelis, Martin, Ehninger, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537224/
https://www.ncbi.nlm.nih.gov/pubmed/28761067
http://dx.doi.org/10.1038/s41467-017-00178-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537224/
https://www.ncbi.nlm.nih.gov/pubmed/28761067
http://dx.doi.org/10.1038/s41467-017-00178-3

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