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PLA(2)R binds to the annexin A2-S100A10 complex in human podocytes

Phospholipase A(2) receptor (PLA(2)R) is a member of the mannose receptor family found in podocytes in human kidney. PLA(2)R is the target of the autoimmune disease, membranous nephropathy, characterised by production of anti-PLA(2)R autoantibodies which bind to the podocyte. However the function of...

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Detalles Bibliográficos
Autores principales: Fresquet, Maryline, Jowitt, Thomas A., McKenzie, Edward A., Ball, Matthew D., Randles, Michael J., Lennon, Rachel, Brenchley, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537237/
https://www.ncbi.nlm.nih.gov/pubmed/28761153
http://dx.doi.org/10.1038/s41598-017-07028-8