The basal translation rate of authentic HIV-1 RNA is regulated by 5’UTR nt-pairings at junction of R and U5

The paradigm protein synthesis rate is regulated by structural complexity of the 5′untranslated region (UTR) derives from bacterial and other riboswitches. In-solution, HIV-1 5′UTR forms two interchangeable long-range nucleotide (nt) -pairings, one sequesters the gag start codon promoting dimerizati...

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Detalles Bibliográficos
Autores principales: Boeras, I., Seufzer, B., Brady, S., Rendahl, A., Heng, X., Boris-Lawrie, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537239/
https://www.ncbi.nlm.nih.gov/pubmed/28761163
http://dx.doi.org/10.1038/s41598-017-06883-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537239/
https://www.ncbi.nlm.nih.gov/pubmed/28761163
http://dx.doi.org/10.1038/s41598-017-06883-9

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