Cargando…
The basal translation rate of authentic HIV-1 RNA is regulated by 5’UTR nt-pairings at junction of R and U5
The paradigm protein synthesis rate is regulated by structural complexity of the 5′untranslated region (UTR) derives from bacterial and other riboswitches. In-solution, HIV-1 5′UTR forms two interchangeable long-range nucleotide (nt) -pairings, one sequesters the gag start codon promoting dimerizati...
Autores principales: | Boeras, I., Seufzer, B., Brady, S., Rendahl, A., Heng, X., Boris-Lawrie, K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537239/ https://www.ncbi.nlm.nih.gov/pubmed/28761163 http://dx.doi.org/10.1038/s41598-017-06883-9 |
Ejemplares similares
-
Specific DNAzymes cleave the 300–618 nt of 5′UTR to inhibit DHAV-1 translation and replication
por: Li, Yanglin, et al.
Publicado: (2022) -
Identification of conserved, primary sequence motifs that direct retrovirus RNA fate
por: Singh, Gatikrushna, et al.
Publicado: (2018) -
HIV-1 hypermethylated guanosine cap licenses specialized translation unaffected by mTOR
por: Singh, Gatikrushna, et al.
Publicado: (2021) -
Before It Gets Started: Regulating Translation at the 5′ UTR
por: Araujo, Patricia R., et al.
Publicado: (2012) -
Cap-independent translation through the p27 5′-UTR
por: Jiang, Hong, et al.
Publicado: (2007)