The neuroprotective effect of hesperidin in NMDA-induced retinal injury acts by suppressing oxidative stress and excessive calpain activation

We found that hesperidin, a plant-derived bioflavonoid, may be a candidate agent for neuroprotective treatment in the retina, after screening 41 materials for anti-oxidative properties in a primary retinal cell culture under oxidative stress. We found that the intravitreal injection of hesperidin in...

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Detalles Bibliográficos
Autores principales: Maekawa, Shigeto, Sato, Kota, Fujita, Kosuke, Daigaku, Reiko, Tawarayama, Hiroshi, Murayama, Namie, Moritoh, Satoru, Yabana, Takeshi, Shiga, Yukihiro, Omodaka, Kazuko, Maruyama, Kazuichi, Nishiguchi, Koji M., Nakazawa, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537259/
https://www.ncbi.nlm.nih.gov/pubmed/28761134
http://dx.doi.org/10.1038/s41598-017-06969-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537259/
https://www.ncbi.nlm.nih.gov/pubmed/28761134
http://dx.doi.org/10.1038/s41598-017-06969-4

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