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The neuroprotective effect of hesperidin in NMDA-induced retinal injury acts by suppressing oxidative stress and excessive calpain activation
We found that hesperidin, a plant-derived bioflavonoid, may be a candidate agent for neuroprotective treatment in the retina, after screening 41 materials for anti-oxidative properties in a primary retinal cell culture under oxidative stress. We found that the intravitreal injection of hesperidin in...
Autores principales: | Maekawa, Shigeto, Sato, Kota, Fujita, Kosuke, Daigaku, Reiko, Tawarayama, Hiroshi, Murayama, Namie, Moritoh, Satoru, Yabana, Takeshi, Shiga, Yukihiro, Omodaka, Kazuko, Maruyama, Kazuichi, Nishiguchi, Koji M., Nakazawa, Toru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537259/ https://www.ncbi.nlm.nih.gov/pubmed/28761134 http://dx.doi.org/10.1038/s41598-017-06969-4 |
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