Homocysteine induces mitochondrial dysfunction involving the crosstalk between oxidative stress and mitochondrial pSTAT3 in rat ischemic brain

Homocysteine (Hcy) has been shown to have a neurotoxic effect on ischemic brain cells; however, the underlying mechanisms remain incompletely understood. Here, we examined whether Hcy treatment influences mitochondria injury, oxidative stress, and mitochondrial STAT3 (mitoStat3) expression in rat is...

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Detalles Bibliográficos
Autores principales: Chen, Shuang, Dong, Zhiping, Zhao, Yaqian, Sai, Na, Wang, Xuan, Liu, Huan, Huang, Guowei, Zhang, Xumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537278/
https://www.ncbi.nlm.nih.gov/pubmed/28761070
http://dx.doi.org/10.1038/s41598-017-07112-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537278/
https://www.ncbi.nlm.nih.gov/pubmed/28761070
http://dx.doi.org/10.1038/s41598-017-07112-z

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