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Membrane Targeting of Disheveled Can Bypass the Need for Arrow/LRP5

The highly conserved Wnt signaling pathway regulates cell proliferation and differentiation in vertebrates and invertebrates. Upon binding of a Wnt ligand to a receptor of the Fz family, Disheveled (Dsh/Dvl) transduces the signal during canonical and non-canonical Wnt signaling. The specific details...

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Detalles Bibliográficos
Autores principales: Kaur, Prameet, Lam, Vanessa Yuk Man, Mannava, Anirudh Gautam, Suresh, Jahnavi, Jenny, Andreas, Tolwinski, Nicholas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537288/
https://www.ncbi.nlm.nih.gov/pubmed/28761148
http://dx.doi.org/10.1038/s41598-017-04414-0