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Improving cartilage phenotype from differentiated pericytes in tunable peptide hydrogels

Differentiation of stem cells to chondrocytes in vitro usually results in a heterogeneous phenotype. This is evident in the often detected over expression of type X collagen which, in hyaline cartilage structure is not characteristic of the mid-zone but of the deep-zone ossifying tissue. Methods to...

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Detalles Bibliográficos
Autores principales: Alakpa, Enateri V., Jayawarna, Vineetha, Burgess, Karl E. V., West, Christopher C., Péault, Bruno, Ulijn, Rein V., Dalby, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537289/
https://www.ncbi.nlm.nih.gov/pubmed/28761049
http://dx.doi.org/10.1038/s41598-017-07255-z