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Dynamics and mechanisms of clonal expansion of HIV-1-infected cells in a humanized mouse model

Combination anti-retroviral therapy (cART) has drastically improved the clinical outcome of HIV-1 infection. Nonetheless, despite effective cART, HIV-1 persists indefinitely in infected individuals. Clonal expansion of HIV-1-infected cells in peripheral blood has been reported recently. cART is effe...

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Detalles Bibliográficos
Autores principales: Satou, Yorifumi, Katsuya, Hiroo, Fukuda, Asami, Misawa, Naoko, Ito, Jumpei, Uchiyama, Yoshikazu, Miyazato, Paola, Islam, Saiful, Fassati, Ariberto, Melamed, Anat, Bangham, Charles R. M., Koyanagi, Yoshio, Sato, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537293/
https://www.ncbi.nlm.nih.gov/pubmed/28761140
http://dx.doi.org/10.1038/s41598-017-07307-4