Scutellarin protects against doxorubicin-induced acute cardiotoxicity and regulates its accumulation in the heart

The clinical use of doxorubicin (DOX) is limited by its dose-dependent cardiotoxicity. The present study investigated the effects of scutellarin against DOX-induced cardiotoxicity in rats using pharmacodynamic and pharmacokinetic approaches. DOX (20 mg/kg) was injected intraperitoneally (i.p.) as a...

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Detalles Bibliográficos
Autores principales: Sun, Xi-Peng, Wan, Li-Li, Yang, Quan-Jun, Huo, Yan, Han, Yong-Long, Guo, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pharmaceutical Society of Korea 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537312/
https://www.ncbi.nlm.nih.gov/pubmed/28315259
http://dx.doi.org/10.1007/s12272-017-0907-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537312/
https://www.ncbi.nlm.nih.gov/pubmed/28315259
http://dx.doi.org/10.1007/s12272-017-0907-0

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