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Scutellarin protects against doxorubicin-induced acute cardiotoxicity and regulates its accumulation in the heart
The clinical use of doxorubicin (DOX) is limited by its dose-dependent cardiotoxicity. The present study investigated the effects of scutellarin against DOX-induced cardiotoxicity in rats using pharmacodynamic and pharmacokinetic approaches. DOX (20 mg/kg) was injected intraperitoneally (i.p.) as a...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Pharmaceutical Society of Korea
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537312/ https://www.ncbi.nlm.nih.gov/pubmed/28315259 http://dx.doi.org/10.1007/s12272-017-0907-0 |