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Immune selection during tumor checkpoint inhibition therapy paves way for NK-cell “missing self” recognition
The ability of NK cells to specifically recognize cells lacking expression of self-MHC class I molecules was discovered over 30 years ago. It provided the foundation for the “missing self” hypothesis. Research in the two past decades has contributed to a detailed understanding of the molecular mecha...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537320/ https://www.ncbi.nlm.nih.gov/pubmed/28699110 http://dx.doi.org/10.1007/s00251-017-1011-9 |