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Blockade of dengue virus infection and viral cytotoxicity in neuronal cells in vitro and in vivo by targeting endocytic pathways

Dengue virus (DENV) infection in neuronal cells was speculated to trigger neuropathy. Herein, we determined the blockade of DENV infection by targeting endocytic pathways in vitro and in vivo. In DENV-infected mouse brains, we previously showed that viral proteins are expressed in neuronal cells aro...

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Detalles Bibliográficos
Autores principales: Ho, Min-Ru, Tsai, Tsung-Ting, Chen, Chia-Ling, Jhan, Ming-Kai, Tsai, Cheng-Chieh, Lee, Yi-Chao, Chen, Chun-Han, Lin, Chiou-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537343/
https://www.ncbi.nlm.nih.gov/pubmed/28761128
http://dx.doi.org/10.1038/s41598-017-07023-z