Salmonella typhimurium-induced IL-1 release from primary human monocytes requires NLRP3 and can occur in the absence of pyroptosis

Large molecular complexes known as inflammasomes regulate the release of IL-1β from immune cells in response to infection and injury. Salmonella typhimurium infection is reported to activate NLRP3 and NLRC4 inflammasomes which are subsequently involved in pyroptosis of the cell and pathogen clearanc...

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Detalles Bibliográficos
Autores principales: Diamond, Catherine E., Leong, Keith Weng Kit, Vacca, Maurizio, Rivers-Auty, Jack, Brough, David, Mortellaro, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537352/
https://www.ncbi.nlm.nih.gov/pubmed/28761045
http://dx.doi.org/10.1038/s41598-017-07081-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537352/
https://www.ncbi.nlm.nih.gov/pubmed/28761045
http://dx.doi.org/10.1038/s41598-017-07081-3

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