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Shift of EMT gradient in 3D spheroid MSCs for activation of mesenchymal niche function

Despite the wide use of mesenchymal stromal cells (MSCs) for paracrine support in clinical trials, their variable and heterogeneous supporting activity pose major challenges. While three-dimensional (3D) MSC cultures are emerging as alternative approaches, key changes in cellular characteristics dur...

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Detalles Bibliográficos
Autores principales: Jeon, Sohee, Lee, Ho-Sun, Lee, Ga-Young, Park, Gyeongsin, Kim, Tae-Min, Shin, Jihye, Lee, Cheolju, Oh, Il-Hoan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537359/
https://www.ncbi.nlm.nih.gov/pubmed/28761088
http://dx.doi.org/10.1038/s41598-017-07049-3