Prion strains depend on different endocytic routes for productive infection

Prions are unconventional agents composed of misfolded prion protein that cause fatal neurodegenerative diseases in mammals. Prion strains induce specific neuropathological changes in selected brain areas. The mechanism of strain-specific cell tropism is unknown. We hypothesised that prion strains r...

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Detalles Bibliográficos
Autores principales: Fehlinger, Andrea, Wolf, Hanna, Hossinger, André, Duernberger, Yvonne, Pleschka, Catharina, Riemschoss, Katrin, Liu, Shu, Bester, Romina, Paulsen, Lydia, Priola, Suzette A., Groschup, Martin H., Schätzl, Hermann M., Vorberg, Ina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537368/
https://www.ncbi.nlm.nih.gov/pubmed/28761068
http://dx.doi.org/10.1038/s41598-017-07260-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537368/
https://www.ncbi.nlm.nih.gov/pubmed/28761068
http://dx.doi.org/10.1038/s41598-017-07260-2

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