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Prion strains depend on different endocytic routes for productive infection
Prions are unconventional agents composed of misfolded prion protein that cause fatal neurodegenerative diseases in mammals. Prion strains induce specific neuropathological changes in selected brain areas. The mechanism of strain-specific cell tropism is unknown. We hypothesised that prion strains r...
Autores principales: | Fehlinger, Andrea, Wolf, Hanna, Hossinger, André, Duernberger, Yvonne, Pleschka, Catharina, Riemschoss, Katrin, Liu, Shu, Bester, Romina, Paulsen, Lydia, Priola, Suzette A., Groschup, Martin H., Schätzl, Hermann M., Vorberg, Ina M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537368/ https://www.ncbi.nlm.nih.gov/pubmed/28761068 http://dx.doi.org/10.1038/s41598-017-07260-2 |
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