Upregulation of UCP2 in beta-cells confers partial protection against both oxidative stress and glucotoxicity

Deterioration of pancreatic beta-cells plays a critical role in the development of type 2 diabetes. Among the various stressors contributing to these deleterious effects, glucotoxicity and superoxides have been proposed as major players. In this context, the mitochondrial uncoupling protein UCP2 is...

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Detalles Bibliográficos
Autores principales: Li, Ning, Karaca, Melis, Maechler, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537434/
https://www.ncbi.nlm.nih.gov/pubmed/28755631
http://dx.doi.org/10.1016/j.redox.2017.07.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537434/
https://www.ncbi.nlm.nih.gov/pubmed/28755631
http://dx.doi.org/10.1016/j.redox.2017.07.012

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