Bayesian association scan reveals loci associated with human lifespan and linked biomarkers

The enormous variation in human lifespan is in part due to a myriad of sequence variants, only a few of which have been revealed to date. Since many life-shortening events are related to diseases, we developed a Mendelian randomization-based method combining 58 disease-related GWA studies to derive...

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Detalles Bibliográficos
Autores principales: McDaid, Aaron F., Joshi, Peter K., Porcu, Eleonora, Komljenovic, Andrea, Li, Hao, Sorrentino, Vincenzo, Litovchenko, Maria, Bevers, Roel P. J., Rüeger, Sina, Reymond, Alexandre, Bochud, Murielle, Deplancke, Bart, Williams, Robert W., Robinson-Rechavi, Marc, Paccaud, Fred, Rousson, Valentin, Auwerx, Johan, Wilson, James F., Kutalik, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537485/
https://www.ncbi.nlm.nih.gov/pubmed/28748955
http://dx.doi.org/10.1038/ncomms15842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537485/
https://www.ncbi.nlm.nih.gov/pubmed/28748955
http://dx.doi.org/10.1038/ncomms15842

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