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Bayesian association scan reveals loci associated with human lifespan and linked biomarkers
The enormous variation in human lifespan is in part due to a myriad of sequence variants, only a few of which have been revealed to date. Since many life-shortening events are related to diseases, we developed a Mendelian randomization-based method combining 58 disease-related GWA studies to derive...
Autores principales: | McDaid, Aaron F., Joshi, Peter K., Porcu, Eleonora, Komljenovic, Andrea, Li, Hao, Sorrentino, Vincenzo, Litovchenko, Maria, Bevers, Roel P. J., Rüeger, Sina, Reymond, Alexandre, Bochud, Murielle, Deplancke, Bart, Williams, Robert W., Robinson-Rechavi, Marc, Paccaud, Fred, Rousson, Valentin, Auwerx, Johan, Wilson, James F., Kutalik, Zoltán |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537485/ https://www.ncbi.nlm.nih.gov/pubmed/28748955 http://dx.doi.org/10.1038/ncomms15842 |
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