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No additional prognostic value for MRE11 in squamous cell carcinomas of the anus treated with chemo-radiotherapy

BACKGROUND: The majority of anal cancers (84–95%) are driven by infection with human papillomavirus (HPV). HPV-positive tumours show significantly better responses to chemo-radiotherapy when compared with HPV-negative tumours. HPV infection is linked to alterations in DNA damage response proteins, i...

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Detalles Bibliográficos
Autores principales: Walker, Alexandra K, Kartsonaki, Christiana, Collantes, Elena, Nicholson, Judith, Gilbert, Duncan C, Kiltie, Anne E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537498/
https://www.ncbi.nlm.nih.gov/pubmed/28641314
http://dx.doi.org/10.1038/bjc.2017.188