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No additional prognostic value for MRE11 in squamous cell carcinomas of the anus treated with chemo-radiotherapy
BACKGROUND: The majority of anal cancers (84–95%) are driven by infection with human papillomavirus (HPV). HPV-positive tumours show significantly better responses to chemo-radiotherapy when compared with HPV-negative tumours. HPV infection is linked to alterations in DNA damage response proteins, i...
Autores principales: | Walker, Alexandra K, Kartsonaki, Christiana, Collantes, Elena, Nicholson, Judith, Gilbert, Duncan C, Kiltie, Anne E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537498/ https://www.ncbi.nlm.nih.gov/pubmed/28641314 http://dx.doi.org/10.1038/bjc.2017.188 |
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