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MRL proteins cooperate with activated Ras in glia to drive distinct oncogenic outcomes

The Mig10/RIAM/Lpd (MRL) adapter protein Lpd regulates actin dynamics through interactions with Scar/WAVE and Ena/VASP proteins to promote the formation of cellular protrusions and to stimulate invasive migration. However, the ability of MRL proteins to interact with multiple actin regulators and to...

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Detalles Bibliográficos
Autores principales: Taylor, E, Alqadri, N, Dodgson, L, Mason, D, Lyulcheva, E, Messina, G, Bennett, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537612/
https://www.ncbi.nlm.nih.gov/pubmed/28346426
http://dx.doi.org/10.1038/onc.2017.68