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The influence of the rs6295 gene polymorphism on serotonin-1A receptor distribution investigated with PET in patients with major depression applying machine learning

Major depressive disorder (MDD) is the most common neuropsychiatric disease and despite extensive research, its genetic substrate is still not sufficiently understood. The common polymorphism rs6295 of the serotonin-1A receptor gene (HTR1A) is affecting the transcriptional regulation of the 5-HT(1A)...

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Detalles Bibliográficos
Autores principales: Kautzky, A, James, G M, Philippe, C, Baldinger-Melich, P, Kraus, C, Kranz, G S, Vanicek, T, Gryglewski, G, Wadsak, W, Mitterhauser, M, Rujescu, D, Kasper, S, Lanzenberger, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537636/
https://www.ncbi.nlm.nih.gov/pubmed/28608854
http://dx.doi.org/10.1038/tp.2017.108